5-Amino-1MQ – 50mg

Research Applications:

NNMT Inhibition Models

5-Amino-1MQ is used in research involving nicotinamide N-methyltransferase (NNMT), an enzyme connected to nicotinamide metabolism, methyl donor balance, and cellular energy regulation [1].
NNMT inhibitor studies often evaluate changes in NAD-related pathways, SAM/SAH balance, and metabolic gene-expression outputs.

Adipocyte and Metabolic Signaling

Because NNMT is studied in adipose and metabolic contexts, 5-Amino-1MQ is positioned for laboratory models that track lipid storage, mitochondrial outputs, and energy-balance markers.

Pathway Screening and SAR

The compound can be used in inhibitor-panel workflows where researchers compare potency, selectivity, and downstream pathway readouts across NNMT-targeted chemotypes [2].

Referenced Citations:

1. NNMT inhibitor design
   Source: PubMed-indexed medicinal chemistry paper on NNMT inhibitor development.
2. NNMT mechanism and inhibitor review
   Source: PubMed-indexed review of NNMT mechanisms and inhibitors.